Vigilancia Tecnológica

An ocular insert, comprising: (a) at least one first mucoadhesive polymer selected from the group consisting of hyaluronic acid or sodium hyaluronate, polyvinylpyrrolidone, carboxyl methyl cellulose, and a combination thereof; (b) at least one second mucoadhesive polymer selected from the group consisting of hydroxyethyl guar, hydroxypropyl guar (HP-guar), hydroxypropyl methylcellulose (HPMC), and a combination thereof; (c) at least one plasticizer and (d) olopatadine in an amount from 2% to 20% by weight of the ocular insert, wherein the ocular insert has no visible recrystallization under examination with a polarized light microscope at approx. 100× magnification, wherein the ocular insert has a single-layer, homogeneous structure, wherein the at least one first mucoadhesive polymer and the at least one second mucoadhesive polymer are together present in the ocular insert in an amount of from about 75% to about 90% by weight of the ocular insert.