Vigilancia Tecnológica

Sprayable HydrogelThis study designs a sprayable hydrogel based on polypeptide?modified lipid nanoparticles (PLNs) to treat non?compressible hemorrhage. Functionalized with GFOGER and GGQQLK peptides, PLNs synergistically mimic natural hemostasis via platelet adherence and aggregation, Ca2+/DSPS?mediated prothrombin activation and fibrin network stabilization. The biomimetic system enables rapid clot formation by sequential coordinating primary hemostasis, coagulation amplification and fibrin reinforcement. More details can be found in article number 2500908 by Yang Li, Chenhui Zhu, Daidi Fan, and co?workers.